The Mayor's Marathon begins at Kincaid Soccer Stadium and finishes at the Park Strip. The race follows the Cook Inlet for 10 miles after the start to West Chester Lagoon. The course then travels along the Chester Creek Trail to Goose Lake and by the ConocoPhillips Integrated Science Building on the Univeristy of Alaska Anchorage campus. The race goes through the Far North Bicentennial Park before returning along Campbell Creek to Westchester Lagoon and the finish at the Park Strip.
The majority of the race is run on paved pedestrian trails.
The double loop Ann Arbor Marathon starts and finishes near The Big House. Participants run through downtown Ann Arbor, then wind their way through the city's streets and parks as well as the University of Michigan campus. The course also encompasses stretches along the Huron River and Gallup Park and through Nichols Arboretum before returning to campus and downtown.